施文瑜

发布时间:2023-07-25录入员:

姓名:施文瑜

职称:教授,主任医师

个人简介:江苏南通人,医学博士。

专业研究领域:血液肿瘤、淋巴瘤。

专著与论集:

1) 郑维成,施文瑜SOD1抑制剂诱导DLBCL细胞凋亡。中国实验血液学杂志 2023

2Yao Wang#, Minan Zhang#, Qingfeng Xue, Huan Zhou, Jie Chen, Hong Wang, Yaping Zhang*, Wenyu Shi*Case Report: Immune Modulation after PD-1 Inhibitor Therapy in a Patient with Extranodal NK/T-cell Lymphoma Secondary to Chronic Active Epstein-Barr Virus Disease Unveiled by Single-Cell Transcriptomics  frontiers in immunology 2023

通讯作者,SCI收录(一区),影响因子:8

3Xiyue Yan#, Juan Liu#, Yu Ben, Weicheng Zheng, Pan Hu, Yaping Zhang*, Wenyu Shi*A rare B-myeloid conversion of follicular lymphoma into clonally related acute myeloid leukemia  Life (Basel). 2023 Mar 8;13(3):729

通讯作者,SCI收录(三区),影响因子:3.2

4Chen W, Ni D, Zhang H, Li X, Jiang Y, Wu J, Gu Y, Gao M, Shi W, Song J,   Wenyu Shi*Over-expression of USP15/MMP3 predict poor prognosis and promote growth, migration in non-small cell lung cancer cells  Cancer Genet. 2023 Jan 7;272-273:9-15.

通讯作者,SCI收录(四区),影响因子:2.1

5Jing He , Qingfeng XueXin Hua , Quanqing LiZiwei Chen, Cindy Zhu and  Wenyu Shi*Association between environmental phenols and allcause and cancer mortality  Environ Sci Pollut Res Int. 2023 Mar;30(12):33432-37

通讯作者,SCI收录(二区),影响因子:5

 

6) 刘娟,颜希月,张亚平,施文瑜18F-FDG PET/CT 在黏膜相关淋巴组织淋巴瘤中的临床应用价值。中国临床研究 2022535649-54

7 Shike Li ,  Qingfeng Xue and  Wenyu Shi* Primary Osteosarcoma of the Breast: A Rare Case Report and Literature Review, Frontiers in oncology,  2022;12:875793.

通讯作者,SCI收录(二区),影响因子: 5

8 Jing He , Ziwei Chen , Qingfeng Xue , Pingping Sun , Yuan Wang , Cindy Zhu and  Wenyu Shi* Identification of molecular subtypes and a novel prognostic model of diffuse large B-cell lymphoma based on a metabolism-associated gene signature  Journal of Translational Medicine,  2022;20:186.通讯作者,SCI收录(一区),影响因子: 8

9 Jing He , Ziwei Chen , Qingfeng Xue  and  Wenyu Shi* Block of Proliferation Promotes Proliferation, Invasion and Epithelial Mesenchymal Transformation in Gastric Cancer  Oxidative Medicine and Cellular Longevity,  2022 Feb 16;2022:2946989.

通讯作者,SCI收录(二区),影响因子: 5

10 Yuan Wang, Jing He, Manyu Xu, Qingfeng Xue, Cindy Zhu, Juan Liu1, Yaping Zhang and Wenyu Shi* Holistic View of ALK TKI Resistance in ALK-Positive Anaplastic Large Cell Lymphoma.  Frontiers in oncology,  2022;12:815654.

通讯作者,SCI收录(二区),影响因子: 5

11 Ziwei Chen, Jing Heand Wenyu Shi* Association between urinary environmental phenols and the prevalence of cardiovascular diseases in US adults  Environmental Science and Pollution Research,  2022; Jan 29.

通讯作者,SCI收录(二区),影响因子: 4

12 Weicheng ZhengQingfeng Xue, Xueping Sha, Yao Wang, Yuan Wang, Juan  Liu, Yaping Zhang, Wenyu Shi  Successful PD-1 Inhibitor Treatment in a Patient With Refractory Transformed Follicular Lymphoma Who Failed to Respond to CAR-T Cell Therapy: A Case Report Journal of Cancer Research and Clinical Oncology. Cancer Biology & Therapy, 2021 Dec 2;22(10-12):537-543.

通讯作者,SCI收录(三区),影响因子: 3

13 Wei Wang, Qianqian Wu, Ziheng Wang, Shiqi Ren, Hanyu Shen, Wenyu Shi and Yunzhao Xu*Development of a Prognostic Model for Ovarian Cancer Patients Based on Novel Immune Microenvironment Related Genes. Frontiers in oncology,  2021;11:647273.

共同通讯作者,SCI收录(二区),影响因子: 6.2

14 Pan HuYuBenJuan LiuWeicheng ZhengXiyue YanYaping ZhangWenyu Shi  Promising Response to Lenalidomide-Combination Therapy in a Discordant Lymphoma Consisting of EBV-Positive Diffuse Large B-Cell Lymphoma and Angioimmunoblastic T-Cell Lymphoma: A Case Report  OncoTargets and Therapy. 2021:14 24892495

通讯作者,SCI收录(三区),影响因子: 4.08

15 Yunzhao Xu Wei WangShuting Gu Qinqin LiuJinling Chen Haixia Mao Yuanlin LiuQinghua XiWenyu Shi  High neuropilin and tolloid-like expression associated with metastasis and poor survival in epithelial ovarian cancer via regulation of actin cytoskeleton. J Cell Mol Med 2020;24:91149124.

通讯作者,SCI收录(二区),影响因子: 4.08

16 Hong Zhou, Pan Hu, Xiyue Yan, Yaping Zhang, and Wenyu Shi. Ibrutinib in Chronic Lymphocytic Leukemia: Clinical Applications, Drug Resistance, and Prospects. OncoTargets and Therapy. 2020:13 48774892

通讯作者,SCI收录(三区),影响因子: 3.08

17Hong Zhou, Li Yang, Qingxiu Dang, Jianfei Huang, Yuehua Cheng, Yaping Zhang, and Wenyu Shi. Ibrutinib resistance in a patient with transformed diffuse large B-cell lymphoma from primary pulmonary mucosa-associated lymphoid tissue lymphoma. Cancer Biol Ther. 2020 Apr 2;21(4):303-308   

通讯作者,SCI收录(三区),影响因子: 3.29

18Bhawana George, Suraj Konnath George, Wenyu Shi, Abedul Haque, Ping Shi, Ghazaleh Eskandari, Magnus Axelson, Olle Larsson, Ahmed O. Kaseb, Hesham M. Amin.  Dual inhibition of IGF-IR and ALK as an effective strategy to eradicate NPM-ALK+ T-cell lymphoma. J Hematol Oncol. 2019 Jul 24;12(1):80.    共同第一作者,SCI收录(一区),影响因子: 11.3

19Qingxiu Dang, Lili Chen, Mengqi Xu, Xuefen You, Hong Zhou, Yaping Zhang, Wenyu Shi The γ-secretase inhibitor GSI-I interacts synergistically with the proteasome T inhibitor bortezomib to induce ALK+ anaplastic large cell lymphoma cell apoptosis. Cellular Signalling 2019 (59):76-84. 通讯作者,通讯作者,SCI收录(二区),影响因子: 3.5

20Qingxiu Dang, Hong Zhou, Juan Qian, Li Yang, Jianfei Huang, Yaping Zhang, Wenyu Shi. LAMP1 Overexpression Predicts Poor Prognosis in Diffuse Large B Cell Lymphoma. Clinical Lymphoma, Myeloma and Leukemia 2018 Nov;18(11):749  通讯作者,SCI收录(三区),影响因子: 2.5

21Yaping Zhang, Xinfeng Wang, Yifei Liu, Chunfeng Sun, Wenyu Shi, Hongming Huang. Lenalidomide combined with R-GDP in a patient with refractory CD5-positive diffuse large B-cell lymphoma: A promising response and review. Cancer Biol Ther. 2018 Jul 3;19(7):549-553.

共同通讯作者,SCI收录(三区),影响因子: 3.29

国际学术会议报告:

1  Wenyu ShiYuan Wang, Yaping Zhang, Haixia Cao and Guangcan Gao. Identification and Verification of Immune-Related Gene Prognostic Signature Based on ssGSEA for DLBCL2023年欧洲血液学年会进行报告,摘要已被会议收录

2  Wenyu Shi Hong Zhou Yaping Zhang Jianfei Huang Pan Hu Jianyong Li. GSK1838705a, an IGF-1R/ALK inhibitor, overcomes crizotinib resistance in ALK+ALCL2019年美国61届血液学年会进行报告,摘要已被Blood收录

3  Wenyu Shi#, Qingxiu Dang, Hong Zhou, Juan Qian, Yaping Zhang. LAMP1 Overexpression Predicts Poor Prognosis in Diffuse Large B Cell Lymphoma 2017年香港李嘉诚医学院郑裕彤奖学金学术报告会壁报交流

 

主要科研项目

主持多项省部级以上科研项目,其中包括国家自然科学基金项目2项。

 

讲授课程

肿瘤学进展

 

指导研究生情况

已毕业硕士生9名;在读博士生3名,硕士生13名。